Diabetes treatment complications
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Definition
Risk Factors
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Treating Complications
Both insulin and oral drugs can lower blood sugar levels
too much, causing hypoglycemia. Hypoglycemia can also occur if a person
with diabetes doesn't eat enough or on time or exercises strenuously
without eating. When blood sugar levels are too low, the first organ
affected is the brain. To protect the brain, the body immediately begins to
manufacture glucose from glycogen stores in the liver. This process
involves the release of epinephrine (adrenaline), which tends to induce
hunger, anxiety, a sense of heightened awareness, and a shaky feeling. The
lack of blood glucose to the brain can cause a headache.
Hypoglycemia must be treated quickly because
within minutes it can become severe,
leading to increasing confusion, coma, and rarely permanent brain injury.
At the first sign of hypoglycemia, the person should eat some form of
sugar. Therefore, people with diabetes should always carry candy, lumps of
sugar, or glucose tablets to treat episodes of hypoglycemia. Other options
are to drink a glass of milk (which contains lactose, a type of sugar),
sugar water, or fruit juice or to eat a piece of cake, some fruit, or other
sweet food. People with type I diabetes should always carry or have
available glucagon (a hormone that raises blood
sugar levels), which can be injected in case they aren't able to take any
food containing sugar.
Diabetic ketoacidosis is a
medical emergency. Without prompt and excellent treatment, diabetic ketoacidosis can cause a coma and death.
Hospitalization, usually in an intensive care unit, is necessary. Large
amounts of intravenous fluids are given along with electrolytes, such as
sodium, potassium, chloride, and phosphate, to replace those lost through
excessive urination. Insulin is generally given intravenously so that it
works quickly and the dose can be adjusted frequently. Blood levels of
glucose, ketones, and electrolytes are measured
every few hours so that doctors can adjust the treatment. Doctors also take
samples of arterial blood to measure its acidity. Sometimes additional
treatments are needed to correct the acidity, although controlling blood
sugar levels and replacing electrolytes usually allow the body to restore
the normal acid-base balance.
The treatment of nonketotic hyperglycemichyperosmolar coma is similar to that of
diabetic ketoacidosis. Fluid and electrolytes must
be replaced. Blood sugar levels must be restored gradually to avoid sudden
shifts of fluid into the brain. Blood sugar levels tend to be more easily
controlled than in diabetic ketoacidosis, and
blood acidity problems are not severe.
Most of the long-term complications of diabetes are
progressive unless the blood sugar level is tightly controlled. Diabetic
retinopathy, however, can be directly treated. Laser surgery can seal the
leaking eye blood vessels to prevent permanent damage to the retina. Early
laser treatment can help prevent or substantially slow the loss of vision.


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